BR+NAD® is more than a treatment — it’s a standard of care.
Developed in 2001 by Paula Norris Mestayer and Dr. Richard Mestayer III, BR+NAD® is the original NAD+ IV protocol proven to support mental health recovery, addiction treatment, neuroprotection, and overall brain restoration. It is the most clinically validated and professionally administered NAD+ treatment model in the world.
BR+NAD® is more than a protocol — it’s a mission.
Meet the BR+NAD® Family
For over two decades, our team has led the field of NAD+ therapy through groundbreaking clinical care, physician training, and scientific research. Today, that mission is carried forward across three organizations:
Springfield Wellness Center — Our original clinic, offering direct-to-patient BR+NAD® therapy.
BR+MD Consultants — Our training and product branch, originally created to teach the BR+NAD® protocol to physicians.
NAD Research, Inc. — A nonprofit conducting essential studies into NAD+’s role in addiction recovery, neurodegenerative disease, mental health, and more.
Each branch plays a vital role — but together, they reflect one unified goal:
To make NAD+ healing accessible, trusted, and grounded in science.
A protocol: Our proprietary NAD+ IV treatment method, administered in clinical settings using carefully researched dosages and timing.
A brand: The trusted name that stands for safety, clinical oversight, integrity, and long-term results in the NAD+ space.
A legacy: The foundation of decades of healing, used in thousands of cases and studied in formal research.
While NAD+ is now used in many clinics and supplements, not all NAD+ therapy is the same.
Medical Oversight
Every BR+NAD® protocol is designed for real clinical settings — not generic wellness menus. Treatment is individualized, physician-guided, and based on established safety parameters.
Precise Protocols
Our dosing schedule, pacing, and NAD+ formulation are based on extensive in-practice experience and formal clinical research. Other clinics often guess. We don’t.
Research-Backed Results
Our treatment outcomes are backed by peer-reviewed studies through NAD Research, Inc. BR+NAD® has been shown to improve outcomes in addiction, PTSD, neurodegenerative illness, and more.
High-Purity Formulations
From IV to spray, all BR+NAD® products are formulated to the highest standard — including our proprietary nanoNAD+ Power Spray, the only true nanoliposomal NAD+ on the market.
Legacy and Experience
Trusted Nationwide
The BR+NAD® protocol has been adopted by trained providers across the country and remains the gold standard for safe, effective NAD+ care. Whether you receive treatment at our flagship Springfield Wellness Center or from an affiliated BR+MD provider, you can trust you’re receiving the real thing — not an imitation.
No shortcuts. No guesswork. Just real science and real results.
NAD-Related Articles
There’s a growing resurgence of interest in NAD+ throughout the medical community — and our research arm, NAD Research, Inc., is leading the way. Through ongoing clinical studies using our proprietary BR+NAD® protocol, we’re uncovering new insights and long-term health applications for this powerful molecule.
To explore the science behind BR+NAD®, visit NAD Research, Inc.